Posted By Clod on April 27, 2012
New insight into the workings of our natural pain relief system was gained in a recent study. Some of the participants in the study had undergone sustained pain. The scientists who performed the study analyzed the chemical activity in the brains of these participants. This study has provided scientists a new method of measuring subjective pain sensations and the manners in which the body responds to pain.
The outcomes of the study verify the link between individual’s feeling during a pain episode and the chemical reaction in the brain during that period. Of course as more people gain knowledge of pain itself, it will lead to better pain remedies. Pain signals are prevented from being relayed to the body by natural endorphins or opioids that are produced by the body. Recent studies reveal that these substances block receptors to the brain.
Participants in the study were subjected to continuous jaw pain for 20 minutes. Chemical data of the brain indicated elevated levels of endorphin substances when the pain started. Once the substance had risen to a high level in the brain, the subjects felt a lesser sensation of pain than previously.
The area of the brain that is recognized as being involved in affective and emotional responses was found to have the highest increase in endorphin levels. This presents scientists better understanding on the close relationship between brain chemistry and emotional behavior.
Similar to synthetic opioids like tramadol, endorphins target specific types of mu opioid receptors inside the brain and thus block pain signals. Nonetheless, the way in which these receptors are distributed in the brain plays a big role in determining how the subject experiences pain and at what level the pain threshold will be established.
A number of researchers have found the mu opioid receptors to be in the greatest concentration around the regions of the brain associated with feelings and emotions.
Some very interesting results came out of the study’s analysis on the chemical responses exhibited by different people. Subjects will naturally experience pain in a variety of ways because of the varying strengths and locations of the pain-receiving mu opioid receptors. Pain ratings are in direct correlation with the subjects’ endorphin levels. A number of the subjects with elevated endorphin production boasted of little pain sensations. When this is the case, the natural pain defenses of the subject work on a par with tramadol hcl 50mg. Other subjects with lesser amounts of endorphins complained of stronger pain. This explains why different people have varying levels of pain tolerance.
Is it possible that buying tramadol is not necessary since our own bodies’ pain-fighting system will do the trick? Why, certainly not. Even for people able to take a lot of pain, some types of pain are very hard to withstand.
Still, the study’s data will allow scientists to better comprehend the functionalities associated with our natural pain relief structure. Eventually, this will translate into more effective pain medications that work in harmony with the body’s own pain relief system. When we discover how to control these inherent systems, medications will no longer be needed. In the meantime, pain relief drugs are our only resort.